American Society for Blood and Marrow Transplantation
RECOMMENDATIONS
1. Expectant parents are encouraged to donate their newborn’s UCB for public banking, when that option is available. Donation makes the CB, which is rich in HSCs, available for life-saving treatments when there is a suitable match with a patient.
2. Private storage of CB for future use by the newborn is not routinely recommended. The likelihood of the stored blood being used for HSCT is very small, probably as low as 0.04% to 0.001% in the first 20 years of life. If later in life a transplant is required, there likely will be superior sources of suitable stem cells than the child’s own CB.
3. Family member banking (collecting and storing CB for a family member) may be recommended for a newborn who has a sibling with a disease that can be successfully treated with HSCT. Family member banking on behalf of a parent with a disease that may be treated successfully with allogeneic transplant is only recommended when there are shared HLA-antigens between the parents.
4. Accurate and complete information about UCB collection and banking should be available to expectant parents so that they can make informed decisions. Parents who choose to store CB for personal use should carefully review their contract and financial responsibilities, and inquire about quality standards, median nucleated cell dose of stored units, and accreditation of the CB bank.
5. The committee acknowledges the potential for an expansion of indications for CB in the future, and these recommendations will be reviewed periodically so that they remain consistent with current medical knowledge.
More Info:
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